Matthew Shannon

Matthew Shannon

Assistant Professor of Biochemistry

Dr. Shannon is a biophysical chemist, who is interested in using spectroscopic methods to study macromolecules at atomic resolution.

  • PhD, chemistry, The Ohio State University
  • BS, chemistry, University of Pittsburgh

Contact

Course Sampling

  • Biochemistry
  • General Chemistry
  • Spectroscopy

Areas of Expertise

  • Biophysical chemistry
  • NMR spectroscopy
  • Protein structure, dynamics, and interactions

Biography

Matthew grew up in Pittsburgh, PA and obtained his undergraduate degree in chemistry at the University of Pittsburgh. He then earned his PhD in physical chemistry at The Ohio State University (OSU) under the supervision of Dr. Christopher Jaroniec. At OSU, he used solid-state Nuclear Magnetic Resonance (NMR) to probe the structure and dynamics of biomolecules (e.g. - chromatin and prion amyloids). After obtaining his PhD, he began his academic career at Denison University. In his two years at Denison as a Visiting Professor, he gained invaluable experience conducting research with undergraduates and teaching introductory chemistry and biochemistry courses. He is excited to bring his interdisciplinary background to Stetson beginning in the fall of 2020. He also enjoys volleyball, basketball, running, watersports, and spending time at the beach. He hopes to find time to do all these activities in sunny Florida.

Research

  • NMR methods to probe protein-ligand interactions
  • Characterization of peptides for models of amyloid fibrils
  • Design of advanced undergraduate labs to improve pedagogy

Publications

  • M.D. Shannon, T. Theint, D. Mukhopadhyay, K. Surewicz, W.K. Surewicz, D. Marion, P. Schanda, C.P. Jaroniec, Conformational dynamics in the core of human Y145Stop prion protein amyloid probed by relaxation dispersion NMR, ChemPhysChem 2019, 20, 311-317.
  • D. Mukhopadhyay, P.S. Nadaud, M.D. Shannon, C.P. Jaroniec, Rapid quantitative measurements of paramagnetic relaxation enhancements in Cu(II)-tagged proteins by proton-detected solid-state NMR spectroscopy, J. Phys. Chem. Lett. 2017, 8, 5871-5877.
  • L.A. Baldwin, J.W. Crowe, M.D Shannon, C.P. Jaroniec, P.L. McGrier, 2D covalent organic frameworks with alternating triangular and hexagonal pores, Chem. Mater. 2015, 27, 6169-6172.
  • T.F. Cunningham, M.D. Shannon, M.R. Putterman, R.J. Arachchige, I. Sengupta, M. Gao, C.P. Jaroniec, S. Saxena, Cysteine specific Cu2+ chelating tags used as paramagnetic probes in double electron electron resonance, J. Phys. Chem. B 2015, 119, 2839-2843.