Kristine Dye

Kristine Dye

Assistant Professor

Dr. Dye is a molecular and cellular biologist who investigates mechanisms by which viruses perturb normal cellular functions resulting in the development of disease and/or cancer. She believes having the perspective of disease allows you to gain a greater understanding and appreciation for the beauty and complexity of Biology. She has a strong belief that topics relating to biology, virology, evolution, and cancer should be accessible and explored by everyone, rather than the few. Such understanding allows students to view the world and its current issues and discoveries in a different, more appreciable light.

  • BS, Microbiology, Brigham Young University - Idaho
  • PhD, Pathobiology, University of Washington

Contact

Course Sampling

  • Introductory Biology I
  • Health and Wellness
  • Viral Spillover
  • Senior Research

Area of Expertise

  • Virology
  • Cancer
  • Molecular Biology
  • Cell Biology

Biography

After growing up in Oviedo, FL, Dr. Kristine Dye moved to the NW to attend Brigham Young University - Idaho in Rexburg, ID. As an undergraduate she was unsure of what career to pursue until she was introduced to microbiology in an undergraduate elective course. Dr. Dye fell in love with the microbiology and quickly changed her major to Biology with a minor in Microbiology, became the university Microbiology Tutor for the next 3 years, and began researching Herpes Simplex Virus reactivation with Dr. Seth Ririe. In 2015, she graduated with a BS in Biology with a minor in Microbiology from BYUI. From here, Dr. Dye went on to pursue her PhD in the interdisciplinary Pathobiology PhD program at the University of Washington in Seattle Washington. There she continued her work on studying viruses, with an emphasis on viruses that cause cancer at the Fred Hutch Cancer Research Center with Dr. Denise Galloway. Dr. Dye's primary research interest is elucidating mechanisms of cellular transformation and tumorigenesis by Merkel cell polyomavirus, the etiologic agent of 80% of Merkel cell carcinomas, a skin cancer 3x more deadly than melanoma. While in graduate school, Dr. Dye continued practicing her love of teaching working as a TA, mentoring graduate, undergraduate, and high school teachers in the lab, and teaching undergraduate courses at UW. She also was accepted and participated in the Science Teaching Experience Program (STEP) and Science Education Partnership (SEP) during her time at UW. In 2020, she graduated with a PhD in Pathobiology from the University of Washington, before starting her career at Stetson University.

Research

  • Merkel Cell Polyomavirus mediated cellular transformation
  • Viral oncoprotein cellular interactors
  • Cellular pathway perturbation by viral oncoprotein

Publications

  • Dye K.N., Welcker M., Clurman B.E., Roman A., Galloway D.A. Merkel cell polyomavirus Tumor antigens expressed in Merkel cell carcinoma function independently of the ubiquitin ligases Fbw7 and beta-TrCP. PLoS Pathog. 2019;15:e1007543. doi: 10.1371/journal.ppat.1007543.