George Huhn

Visiting Assitant Professor of Biology

  • PhD, Biomedical Sciences, University of Central Florida, 2022
  • MS, Biotechnology, University of Central Florida, 2019
  • BS, Biomedical Sciences, University of Central Florida, 2016

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More About George Huhn

Areas of Expertise

  • Cellular Microbiology
  • Toxin-cell biology
  • Host-pathogen interactions

Course Topics

  • BIOL 121
  • BIOL 141
  • BIOL 142

  • How bacterial toxins exploit common cellular processes to elicit either a Cytotoxic or Cytolethal effect
  • Gram-negative bacterial toxins protein structures
  • Toxin transport mechanisms after Endocytosis into a host cell

  • Robb Huhn G 3rd, Torres-Mangual N, Clore J, Cilenti L, Frisan T, Teter K. Endocytosis of the CdtA subunit from the Haemophilus Ducreyi Cytolethal distending toxin. Cell Microbiol. 2021 Nov, 23. Epub 2021 Aug 11. PMID: 34292647.
  • Huhn GR 3rd, Sparkes C*, Silva I*, Reyes C*, Perez G*, Khondker F*, Jones T*, Fragoso A*, Contreras P*, Alvarez M*, Zabala-Rodriguez MC, Tatulian SA, Teter K. Acid-induced disassembly of the Haemophilus Ducreyi Cytolethal distending toxin. Biochem Biophys Res Commun. 2022 Dec 25;636(Pt 1):57-63. PMID: 36332483.
  • J. Guyette, A. Serrano, GR Huhn III, M. Taylor, P. Malkm, D. Curtis, and K Teter. Reduction is Sufficient for the Disassembly of Ricin and Shiga Toxin 1 but not Escherichia coli Heat-Labile Enterotoxin. Infection and Immunity. Submitted Aug. 2023.