Latifa Abdelli

Latifa Abdelli

Visiting Assistant Professor of Health Sciences

Latifa S. Abdelli, Ph.D., is a Visiting Assistant Professor in the Health Science department. She teaches Anatomy & Physiology I & II (HLSC 201 & 202), Research Proposal and Project (HLSC- 498 & 988), as well as Medical Terminology (HLSC - 441) courses. Abdelli's research portfolio includes clinical auto-immune disorders such as inflammatory bowel disease, rheumatoid arthritis, autism spectrum disorder, diabetes, and other cardio-metabolic disorders. All of which, she believes, stems from an environmental-induced shift in the gut brain-axis.

  • P3 preeminent post-doctoral awardee- Burnett School of Biomedical Sciences-College of Medicine-University of Central Florida- 2017
  • PhD and MS, biomedical sciences, Burnett School of Biomedical Sciences-College of Medicine-University of Central Florida
  • BS, biology - genetics, University of Science and Technology Houari Boumediene, Algiers, Algeria

Contact

Course Sampling

  • Anatomy and Physiology I & II
  • Research Proposal
  • Research Project
  • Medical Terminology

Areas of Expertise

  • Stem cells in tissue repair and regeneration
  • Diet in Gut-Brain axis health and disease
  • Diet in neurodevelopmental disorders

Biography

Latifa S. Abdelli, Ph.D., is originally from Algeria where she obtained her Bachelor's degree in Biology Genetics at the University of Science and Technology Houari Boumediene, (Summer 2006). Her Master's and Ph.D. in Biomedical Sciences were granted by the University of Central Florida School of Medicine in 2014 and 2015, respectively. From 2015 to 2017, Abdelli coordinated the animal research program at UCF before receiving the prestigious P3 postdoctoral research award at UCF in 2017. During her postdoctoral years, along with actively engaging in bench work research, Abdelli cofounded and directed the UCF-postdoctoral association for two years. She began her academic career at Stetson University in 2020, where she was an adjunct faculty in the health sciences department for a semester and hired thereafter as a visiting assistant professor in the spring of 2021 to take on Anatomy & Physiology I & II (HLSC 201 & 202), research proposal and project ( HLSC- 498 and 988), as well as Medical Terminology (HLSC - 441) courses.

Abdelli's research portfolio includes clinical auto-immune disorders such as inflammatory bowel disease, rheumatoid arthritis, autism spectrum disorder, diabetes and other cardio-metabolic disorders. All of which she believes stem from a shift in the gut brain-axis.

Research

Understanding the role of gut dysbiosis and resulting metabolites in the pathophysiology of inflammatory diseases such as Crohn's disease (CD), Type I Diabetes (T1D), Autism Spectrum Disorder (ASD) and cardio-metabolic disorders.

Publications

  • AlQasrawi, D., Abdelli, L. S., & Naser, S. A. (2020). Mystery Solved: Why Smoke Extract Worsens Disease in Smokers with Crohn's Disease and Not Ulcerative Colitis? Gut MAP!. Microorganisms, 8(5), 666.
  • Abdelli LS, Samsam A, Naser SA. Propionic Acid Induces Gliosis and Neuro-inflammation through Modulation of PTEN/AKT Pathway in Autism Spectrum Disorder. Sci Rep. 2019 Jun 19;9(1):8824. doi: 10.1038/s41598-019-45348-z. PMID: 31217543; PMCID: PMC6584527.
  • Sharp, R. C., Naser, E. S., Alcedo, K. P., Qasem, A., Abdelli, L. S., & Naser, S. A. (2018). Development of multiplex PCR and multi-color fluorescent in situ hybridization (m-FISH) coupled protocol for detection and imaging of multi-pathogens involved in inflammatory bowel disease. Gut pathogens, 10(1), 51.
  • Cao BL, Qasem A, Sharp RC, Abdelli LS, Naser SA. Systematic review and meta-analysis on the association of tuberculosis in Crohn's disease patients treated with tumor necrosis factor-α inhibitors (Anti-TNFα). World J Gastroenterol 2018; 24(25): 2764-2775.
  • Abdelli LS and Singla DK. A CD63(+ve)/c-kit(+ve) stem cell population isolated from the mouse heart. Mol Cell Biochem. 2015 Aug;406(1-2):101-9. doi: 10.1007/s11010-015-2428-9. Epub 2015 Apr 29.
  • Singla DK, Singla RD, Abdelli LS, and Glass CE. Fibroblast Growth Factor- 9 Reduces Infarct Size and Improves Heart Function by Mediating M2 Macrophage Differentiaton in the Infarcted Diabetic Heart. PLoS One. 2015 Mar 13;10(3):e0120739. doi: 10.1371/journal.pone.0120739. eCollection 2015.
  • Singla DK and Abdelli LS. Embryonic Stem Cells and Released Factors Stimulate c-kit+ve/FLK-1+ve Progenitor Cells and Promote Neovascularization in Doxorubicin-induced Cardiomyopathy. Cell Transplant. 2014 Mar 3. PMID:24593859.
  • Yan B, Singla RD, Abdelli LS, Singal PK, Singla DK. Regulation of PTEN/Akt Pathway Enhances Cardiomyogenesis and Attenuates Adverse Left Ventricular Remodeling following Thymosin β4 Overexpressing Embryonic Stem Cell Transplantation in the Infarcted Heart. PLoS One. 2013 Sep 24;8(9):e75580. doi: 10.1371/journal.pone.0075580.
  • Yan B, Abdelli LS, Singla DK. Transplanted induced pluripotent stem cells improve cardiac function and induce neovascularization in the infarcted hearts of db/db mice. Mol Pharm. 2011 Oct 3;8(5):1602-10. doi: 10.1021/mp2003576. Epub 2011 Sep 8.
  • Abdelli LS, Merino H, Rocher CM and Singla DK. Cell Therapy in the Heart. Can J Physiol Pharmacol. 2012 Mar; 90(3):307-15.