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Ryan McCleary

Brown Visiting Teacher Scholar Fellow in Biology

Ryan McCleary has been captivated by reptiles (especially snakes) and amphibians since a very early age. This fascination has led him to study snakes at many different levels, from characterizing proteins in venoms to examining the ecology of snake assemblages, in different areas of the world--from the swamps of Florida to the mangroves of Singapore.

Specifically, McCleary is interested in the evolution of venom in snakes and in understanding its complexity at various levels of biological organization. He does this utilizing field studies and various laboratory "-omics" technologies.

Education

  • Postdoctoral Fellow, Utah State University
  • Postdoctoral Fellow, National University of Singapore
  • Ph.D., zoology, University of Florida
  • M.S., biology, Virginia Tech
  • B.S., biology, Western Michigan University

Course Topics

  • Introductory Biology
  • Biostatistics

Select Publications

  • Choudhury, M, RJR McCleary, M Kesherwani, RM Kini, and D Velmurugan. 2017. Comparison of proteomic profiles of the venoms of two of the 'Big Four' snakes of India, the Indian cobra (Naja naja) and the common krait (Bungarus caeruleus), and analyses of their toxins. Toxicon 135:33-42.
  • McCleary, RJR, S Sridharan, N Dunstan, P Mirtschin and RM Kini. 2016. Proteomic comparisons of venoms of long-term captive and recently wild-caught Eastern brown snakes (Pseudonaja textilis) indicate venom does not change due to captivity. Journal of Proteomics 144:51-62.
  • McCleary, RJR, TS Kang and RM Kini. 2015. Reptile venoms as a platform for drug development. In: Venoms to drugs: venom as a source for the development of human therapeutics (G. King, ed). Cambridge: Royal Society of Chemistry, pp. 129-162.
  • Brahma, RK, RJR McCleary, RM Kini, and R Doley. 2015. Venom gland transcriptomics for identifying, cataloging, and characterizing venom proteins in snakes. Toxicon 93(1):1-10.
  • Quesada, R, RJR McCleary, DJ Heard and HB Lillywhite. 2014. Non-lethal liver tissue sampling for toxicologic evaluation in Florida cottonmouths Agkistrodon piscivorus conanti. Ecotoxicology 23(1):33-37.
  • McCleary, RJR and RM Kini. 2013. Snake bites and hemostasis/thrombosis. Thrombosis Research 132(6):642-646.
  • McCleary, RJR and RM Kini. 2013. Non-enzymatic proteins from snake venoms: a gold mine of pharmacological tools and drug leads. Toxicon 62:56-74.
  • Vonk, FJ, NR Casewell, CV Henkel, A Heimberg, HJ Jensen, RJR McCleary, HME Kerkkamp, R Vos, I Guerreiro, JJ Calvete, W Wüster, AE Woods, JM Logan, RA Harrison, TA Castoe, APJ de Koning, DD Pollock, M Yandell, D Calderon, C Renjifo, RB Currier, D Salgado, D Pla, L Sanz, AS Hyder, JMC Ribeiro, JW Arntzen, GEEJM van den Thillart, M Boetzer, W Pirovano, RP Dirks, HP Spaink, D Duboule, E McGlinn, RM Kini and MK Richardson. 2013. The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system. Proceedings of the National Academy of Sciences, USA 110(51):20651-20656.
  • McCleary, RJR and DJ Heard. 2010. Venom extraction from anesthetized Florida cottonmouths, Agkistrodon piscivorus conanti, using a portable nerve-stimulator. Toxicon 55:250-255.
  • Lillywhite, HB and RJR McCleary. 2008. Trophic ecology of insular cottonmouth snakes: review and perspective. South American Journal of Herpetology 3(2):175-185.

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